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  KHV was first reported in 1998 in Israel and in the US. Then numerous cases were reported from a lot of countries with carp industry. Today KHV has been recorded in almost 20 countries in Europe as well as in Asia. KHV has now been recognized by the OIE organization and the cases has to be reported to the local authorities.  
  KHV etiological agent, an herpes virus, was first isolated in 2000 in Great Britain. It’s an herpes virus belonging to the herpesviridae family and characterized by a double strand linear DNA fragment in an icosahedric capsid. The genome size is estimated to 270-290 Kbp. The virus is isolated from grass carps as well as fancy carps (Koi carp).  
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Order analysis (pdf format)
  Global distribution  
  VNN (Viral nervous necrosis) has been reported from all continents and nodavirus is known to affect a large variety of marine fish worldwide.  
  Nodavirus is the aetiological agent of VNN, also called VER (viral encephalopathy and retinopathy). Betanodavirus are small, spherical, non-enveloped viruses with a positive-sense RNA molecule. Betanodavirus have been classified based on the study of the variable region of the coat protein gene into 4 groups: striped jack nervous necrosis virus (SJNNV), barfin flounder nervous necrosis virus (BFNNV), tiger puffer nervous necrosis virus (TPNNV) and red-spotted grouper nervous necrosis virus (RGNNV).  
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ELISA sampling informations (pdf format)
PCR sampling informations (pdf format)
Order analysis (pdf format)
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